The effects of TM on a person depend on which spinal cord segments are damaged. Transverse Myelitis (TM) is when the spinal cord becomes inflamed, causing interruptions to nerve signals sent from the brain to the body, which can create a variety of symptoms. 6 Some patients complain of a headache around the eye or at the front of the head a few days before vision is affected. It is recurrent or bilateral/simultaneous in approximately 50% of all cases. Optic neuritis is the most common MOGAD presentation among adult patients. 1 2 5 Vision loss is usually temporary in some cases, it can be permanent and takes hours or days to happen and weeks to improve. Some people also report seeing flickering, flashing, or sparkles when moving their eyes. Vision loss from optic neuritis can present as loss of central or peripheral vision, colour, or visual acuity.

Other symptoms include vision loss which can be either temporary or permanent depending on the nerve damage. 1 5 A common symptom of ON is eye pain, which can worsen when the eye moves. Optic neuritis (ON) is when the eye's optical nerve(s) becomes inflamed due to damage to the myelin surrounding the nerves in one or both eyes simultaneously. The most common presentation is Optic Neuritis (ON), followed by Transverse Myelitis (TM) and then Acute Disseminated Encephalomyelitis (ADEM). Symptoms of MOG Antibody disease can present differently from person to person.

Mog antibody disease symptoms